NeurAxon Product Overview
"NeurAxon" is a dietary supplement with neuroprotective properties.* NeurAxon has an action on brain cells, promoting their function by helping maintain their integrity.*
What is citicoline?
Citicoline, also known as CDP-choline is an essential nutrient that plays a vital role in the healthy functioning of the body. It is a fundamental compound that the body produces naturally and is found in every cell. In fact, it accounts for 50% of the total membrane phospholipid content of all human cells and constitutes approximately 30% of the gray matter in the human brain.
Medical research has demonstrated that citicoline is especially important to the health and repair of brain cells or neurons.
By taking NeurAxon, the body's supply of citicoline can be increased to help restore its balance within the body: Research documents that citicoline taken orally is effectively absorbed into the body, readily synthesized, passes through the blood-brain barrier into the brain, whereupon it increases brain citicoline levels and then functions as citicoline produced naturally by the body.
"Forgetful? Lost your mental sharpness? NeurAxon™ helps to strengthen and repair brain cells and the connections between them.* "
What Does Citicoline Do?
Research has shown citicoline to be crucial to brain cells in a number of ways including:
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Cell metabolism - the process of cell functioning. Citicoline helps regulate the cell's energy production and use of nutrients for its function.
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Maintaining integrity of the cell membrane - supporting the structure, growth and repair of the cell wall; without adequate citicoline levels, cell walls are unstable and deteriorate.
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Neurotransmission - acting as one of the brain's main signaling agents and positively influencing others, citicoline helps brain cells to communicate between themselves and function effectively.
NeurAxon Supplement Facts
| Supplement Facts |
|---|
|
Serving Size 1 Tablet Serving per container: 30 |
| Amount per serving |
| Citicoline Sodium (CDP-choline Sodium) 500 mg* |
| * Daily Value not established |
Dosage: Citicoline, 500 mg.
Size: 30 Tablets.
Suggested Usage
Most people will take one (1) tablet a day.
NeurAxon does not need to be taken with food.
Other Ingredients
Microcrystalline cellulose, corn starch, croscarmellose sodium, partially hydrolyzed polyvinyl alcohol, titanium dioxide, talc, magnesium stearate, colloidal silicon dioxide, soy lecithin and xanthan gum. Contains Soy Lecithin.
Does NOT contain: wheat, gluten, dairy, egg, fish/shellfish, peanuts/tree nuts.
This product is suitable for vegetarians/vegans.
NeurAxon Clinical Studies
Citicoline improves memory performance in elderly subjects.
Meth Find Exp Clin Pharmacol 1997; 19:201-10.
Abstract
Citicoline is a choline donor involved in the biosynthesis of brain phospholipids and acetylcholine extensively used in the treatment of neurodegenerative diseases. In this study we investigated the effects of the oral administration of citicoline alone (C1000:1000 mg/day; C500:500 mg/day) or in combination with nimodipine (C +NI:300 + 90 mg/day) during 4 weeks on memory performance in elderly subjects with memory deficits and without dementia (N = 24; age = 66.12 +/- 10.78 years; MMS score = 31.69 +/- 2.76).
Results indicated that citicoline in comparison with placebo improves memory in free recall tasks, but not in recognition tests. A significant improvement in word recall (5.17 +/- 1.1 vs. 3.95 +/- 1.2 omissions; p < 0.005), immediate object recall (6.5 +/- 1.6 vs. 5.5 +/- 1.2 omission; p < 0.05) and delayed object recall (8.5 +/- 2.1 vs. 6.7 +/- 2.4 omissions; p < 0.005) was observed after citicoline treatment.
Similar results were found in the three subgroups of treatment (8 subjects per group), suggesting that citicoline possesses memory-enhancing activity at doses of 300-1000 mg/day. A decrease in systolic blood pressure and minor changes in lymphocyte cell counting were also observed in old subjects after receiving citicoline. These effects are consistent with the vasoregulatory and neuroimmune actions of citicoline and suggest that this compound may improve memory by acting on mechanisms of brain neurotropism and cerebrovascular regulation. According to the present results, showing that citicoline improves memory performance in elderly subjects, we concluded that this molecule is suitable for the treatment of memory deficits in old people.
Psychopharmacology (2002) 161:248–254
DOI 10.1007/s00213-002-1045-y
S.M. Babb • L.L. Wald • B.M. Cohen
R.A. Villafuerte • S.A. Gruber • D.A. Yurgelun-Todd
P.F. Renshaw
Chronic citicoline increases phosphodiesters in the brains of healthy older subjects: an in vivo phosphorus magnetic resonance spectroscopy study
Abstract Rationale:
Phosphatidylcholine (PtdCho) in brain cell membranes decreases with age. Evidence from both animal and in vitro studies indicates that CDP-choline (citicoline) administration may increase phosphatidylcholine (PtdCho) synthesis and might reverse PtdCho loss. Objectives: We investigated whether oral citicoline can increase PtdCho synthesis in the brains of older subjects by measuring levels of phosphorus-containing metabolites using proton-decoupled phosphorus magnetic resonance spectroscopy (31P-MRS) before and after citicoline treatment. Methods: All subjects took 500 mg citicoline once orally each day for 6 weeks, then took either citicoline or placebo once orally per day for a second 6-week period. Subjects underwent a 31P-MRS scan at baseline and following 6 and 12 weeks of treatment.
Results:s
Results indicated that citicoline in comparison with placebo improves memory in free recall tasks, but not in recognition tests. A significant improvement in word recall (5.17 +/- 1.1 vs. 3.95 +/- 1.2 omissions; p < 0.005), immediate object recall (6.5 +/- 1.6 vs. 5.5 +/- 1.2 omission; p < 0.05) and delayed object recall (8.5 +/- 2.1 vs. 6.7 +/- 2.4 omissions; p < 0.005) was observed after citicoline treatment.
Treatment with citicoline for 6 weeks was associated with a 7.3% increase from baseline levels in brain phosphodiesters (P=0.008), including an 11.6% increase in glycerophosphoethanolamine (P=0.002) and a 5.1% increase in glycerophosphocholine (P=0.137). Subjects who continued to take citicoline for the second 6-week period did not show significant additional increases in the levels of these metabolites. No changes were seen in other phosphorus-containing metabolites. There was a correlation between improvement on the California Verbal Learning Test and increase in phosphodiesters.
Conclusions:
The increases in phosphodiesters seen in this study indicate that phospholipid synthesis and turnover were stimulated by 6 weeks of oral citicoline. These results in humans support previous in vitro and animal studies and suggest that the administration of oral citicoline may be of use in reversing age-related changes in the brain.
NeurAxon Product Review
It was very interesting because I really didn't know there was anything over the counter like athat. The age that I'm at now, I'm starting to feel the effects of missing items or not being able to recall names so it definitely piqued my interest.
5 stars
-Melissa Anderson, Age 45-54
I told him (my husband) how excited I was not only for him but for me also. I thought it would be a great thing to take so that it would help us both.
He thought that was great. He started taking it and I don't know if I see 100 percent improvement, but at the same time, we had started doing all this exercise and he seems to be able to concentrate on something for a little bit more, like a crossword puzzle. I don't know if that's just my imagination or if that's really what's happening.
5 stars
-Adam Charlie & Kiera Linton, Spouse
I've become more focused on what I should be doing, and that's helping me to motivate and follow through with what I need to do.
5 stars
-Kelly Tan, Age 45-54
I have and I didn't notice it the first week or so. It's funny. I mean I have noticed. I definitely have, and it's more of – it's so hard to describe because I'm doing more things now too. I'm in this big health mode so I'm trying to exercise more. I do feel good though. I definitely feel my concentration's better. I'm listening to people and I'm not as distracted. I don't have that fogginess. I absolutely feel better. I absolutely do. I am a person that's benefit from NeurAxon. Sometimes I feel like the supplements that I take don't have an effect or not something that really entices me to continue. I actually feel pretty good about this product.
5 stars
-Tim Cahill, Son
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Who are we?
"Ferrer Therapeutics, Inc." is the US subsidiary of Ferrer Grupo, an international pharmaceutical group that works in the fields of prescription, diagnosis, hospitals and personal healthcare.
Ferrer Grupo operates throughout the pharmaceutical value chain, with activities ranging from the research and development of new drugs to the industrial production and marketing of new products, while always maintaining a strong commitment both to society and to the environment. Currently, Ferrer Grupo has around 2,000 employees, of which over 200 work in R&D.
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NeurAxon :: Dietary Memory Supplement, Protects & Improves Brain Function!
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